This deficiency contributes to general signs of illness, and the condition may become life-threatening if the hormone levels drop too low. These hormones regulate life-sustaining functions - including electrolytes, blood pressure, hydration, metabolism and stress responses.Īddison’s disease is caused by a lack of cortisol and aldosterone hormones. The adrenal glands are small organs next to the kidneys, and the glands produce essential hormones, including glucocorticoid (cortisol) and mineralocorticoid (aldosterone). After being diagnosed and stabilized with medications, the outcome is very good - provided that you follow your veterinarian’s recommendations for continued treatment and monitoring. However, if a dog’s hormone levels become critically low, Addison’s disease can become an acute and life-threatening condition.Īddison’s disease is more common in young or middle-aged dogs, and while either sex can be affected, females may be at an increased risk. Hypoadrenocorticism is an uncommon disease in dogs, and it is caused by a deficiency of essential hormones that are made by the adrenal glands.Īlso known as Addison’s disease, the clinical signs may appear as vague signs of illness that come and go.